Cancer Imaging Phenomics Toolkit (CaPTk)  1.8.0.Beta
Histogram Matching

This tool normalizes the intensity profile of an input image based on the intensity profile of a reference image [1].


  1. A reference and an input image.


  1. Launch the tool using the 'Preprocessing' -> 'HistogramMatching' menu option.
  2. Specify the Reference and Input images, and the output filename.
  3. Click on 'Confirm'.
  4. The output image is saved in the specified folder.
  5. This can also be used from the command line:
    ${CaPTk_InstallDir}/bin/Preprocessing.exe -i C:/test/input.nii.gz -o C:/test/output.nii.gz -hi C:/test/target.nii.gz -hb 100 -hq 50


  1. L.G.Nyul, J.K.Udupa, X.Zhang, "New Variants of a Method of MRI Scale Standardization", IEEE Trans Med Imaging. 19(2):143-50, 2000, DOI:10.1109/42.836373